14+ hour, 53+ min ago  (181+ words) Spinal cord stimulation (SCS) is an established therapy for chronic pain, primarily used for analgesia; however, its broader physiologic effects remain poorly characterized. This retrospective observational cohort study evaluated whether SCS implantation was associated with changes in appetite and body…...

1+ day, 14+ hour ago  (155+ words) The evolution of shoulder arthroscopy from inpatient to outpatient settings has necessitated the development of advanced regional anesthesia techniques that provide reliable intraoperative analgesia and hemodynamic stability while minimizing respiratory complications associated with conventional interscalene brachial plexus blocks, which are…...

1+ day, 14+ hour ago  (251+ words) Ochronosis is a rare metabolic disorder caused by alkaptonuria, resulting in the accumulation of homogentisic acid within connective tissues and progressive degeneration of large joints. Clinical presentation often mimics primary osteoarthritis, leading to delayed or missed diagnosis. We report the…...

1+ day, 14+ hour ago  (180+ words) Complex Regional Pain Syndrome (CRPS) is an uncommon and potentially debilitating neuropathic pain condition that may develop after surgical or iatrogenic nerve injury. Although CRPS predominantly affects the extremities, pelvic and perineal involvement is rare and poorly characterized. We report…...

1+ day, 1+ hour ago  (1521+ words) Post-dural puncture headache (PDPH) is a common complication of neuraxial anesthesia, particularly in the obstetric population, where its incidence is higher due to the frequent use of epidural techniques and the occurrence of accidental dural puncture. The condition arises from…...

1+ day, 14+ hour ago  (173+ words) Traditional osteoarthritis (OA) treatment focuses on symptom management, including nonsteroidal anti-inflammatory drugs (NSAIDs), duloxetine, intra-articular glucocorticoids, or surgical intervention. Unfortunately, these approaches may provide inadequate symptom relief or can be contraindicated in patients with comorbidities such as cardiac issues, diabetes,…...

2+ day, 14+ hour ago  (219+ words) Migraine, a primary headache disorder, is a prevalent and debilitating chronic neurologic disorder. Migraine headaches are bidirectionally related to psychiatric conditions, such as anxiety and depression. Given these associations, further investigation into how medications used for migraine prophylaxis are associated…...

2+ day, 14+ hour ago  (289+ words) Background and aim Postoperative pain following root canal treatment (RCT) can be influenced by the obturation technique, as variations in apical sealing and material extrusion may affect periapical tissue response. The aim of this study was to evaluate postoperative pain…...

3+ day, 14+ hour ago  (284+ words) Introduction: Designing effective digital rehabilitation educational content requires alignment between platform functionality and the patient's digital behavior. However, there is limited evidence regarding the platforms selected for structured rehabilitation education following anterior cruciate ligament reconstruction (ACLR). Therefore, this study aimed…...

3+ day, 9+ hour ago  (344+ words) Background Periarticular local infiltration analgesia (LIA) is widely used within multimodal and'enhanced recovery after surgery (ERAS)-based pathways for total knee arthroplasty (TKA). However, real-world data remain heterogeneous, particularly regarding simplified injection regimens without adjuvants. This study aimed to describe…...