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Migration of Cemented and Uncemented Implants in Total Knee Arthroplasty with an Asymmetrical Tibial Component: A Randomized Controlled Trial with a 2-Year Model-Based. ..
8+ mon, 2+ week ago (47+ words) The Nature Index tracks the affiliations of high-quality scientific articles. Updated monthly, the Nature Index presents research outputs by institution and country. Use the Nature Index to interrogate publication patterns and to benchmark research performance. View the latest institution rankings…...
Microsomal Prostaglandin E Synthase and Anti-Inflammatory Drug Development
9+ mon, 2+ day ago (577+ words) Microsomal prostaglandin E synthase-1 (m PGES-1) plays a pivotal role in the biosynthesis of prostaglandin E" (PGE"), a key mediator of inflammation, pain and fever. Unlike conventional non-steroidal. .. Microsomal Prostaglandin E Synthase and Anti-Inflammatory Drug Development Microsomal prostaglandin E synthase…...
Anti-Inflammatory Compounds and Crystal Structure Analysis
9+ mon, 2+ day ago (339+ words) Recent advances in the field of bioactive compounds have underscored the therapeutic potential of anti-inflammatory agents in mitigating chronic and acute inflammatory responses. Increasingly, studies. .. Anti-Inflammatory Compounds and Crystal Structure Analysis Recent advances in the field of bioactive compounds have…...
Anti-Inflammatory Drugs and Cyclooxygenase Inhibitors
9+ mon, 2+ day ago (391+ words) Anti-inflammatory drugs have long served as a cornerstone in the treatment of conditions marked by inflammation, pain, and fever. At the heart of many of these therapeutic agents lies the inhibition. .. Anti-Inflammatory Drugs and Cyclooxygenase Inhibitors Anti-inflammatory drugs have long…...
Peptide-based targeted drug delivery strategies for osteoarthritis treatment - npj Biomedical Innovations
1+ week, 1+ day ago (1659+ words) No datasets were generated or analysed during the current study. Tang, S. et al. Osteoarthritis. Nat. Rev. Dis. Prim. 11, 10 (2025). Rainbow, R. , Ren, W. & Zeng, L. Inflammation and joint tissue interactions in OA: implications for potential therapeutic approaches. Arthritis 2012, 741582 (2012). Mehta, S. , He, T. & Bajpayee, A. G. Recent advances in…...
Longitudinal associations between BMI changes and musculoskeletal pain in older European males and females - International Journal of Obesity
1+ week, 3+ day ago (1505+ words) International Journal of Obesity (2026)Cite this article Musculoskeletal pain affects nearly 200 million European citizens and is a leading cause of disability. This study examines the associations between body mass index (BMI) trajectories over time and self-reported musculoskeletal pain, and explores…...
Super-potent opioids could be safer-than-expected alternatives to conventional painkillers
2+ week, 2+ day ago (337+ words) Emmanuel Darcq is in the National Institute of Health and Medical Research (INSERM) unit UMR-S1329, Strasbourg Translational Neuroscience & Psychiatry, University of Strasbourg (UNISTRA), Strasbourg 67084, France. Darcq, E. & Kieffer, B. L. Nature Rev. Neurosci. 19, 499514 (2018). Mathis, V. P. , Ehrlich, A. T. & Darcq, E. Nature Rev. Neurosci. 26, 778797 (2025). Kieffer, B. L. & Evans, C. J. Cell 108, 587590 (2002). Manglik,…...