1+ day, 13+ hour ago  (235+ words) A randomized trial conducted by the Alliance for Clinical Trials in Oncology with support from the National Cancer Institute has found that duloxetine, a medication commonly used to treat chronic pain and psychiatric conditions, does not prevent nerve damage caused…...

2+ day, 13+ hour ago  (196+ words) Tackling Pain After Lung Surgery Results: Less Opioid Use, Better Recovery Side Effects and Safety DS did cause a higher rate of mild dizziness compared to placebo, mainly during the peak absorption period, but no serious adverse events or significant…...

2+ day, 13+ hour ago  (641+ words) Hand-foot syndrome is a painful side effect commonly seen with chemotherapy drugs like capecitabine. Evidence suggests that an over-the-counter topical gel can help reduce the risk. Specifically, diclofenac gel and the flavonoid silymarin (milk thistle) have shown effectiveness in preventing…...

1+ week, 2+ day ago  (145+ words) The key findings of the study were: " Seventeen studies (1, 705 patients: QT = 765, HT = 725, BTB = 215) with follow-ups through 48 months were included. Due to data heterogeneity, four to six studies qualified for each meta-analysis. " Among 13 QT vs. HT studies, QT grafts demonstrated weaker…...

1+ week, 13+ hour ago  (175+ words) Why Cerebral Hemodynamics Matter in Spine Surgery Study Design: Tracking Brain Blood Flow in Real Time Key Findings: Prone Position Does Not Significantly Alter Cerebral Hemodynamics This suggests that, for patients without significant comorbidities and with well-managed anesthesia and fluid…...

1+ week, 13+ hour ago  (272+ words) Medical Dialogues According to a new research, Topical epinephrine and oxymetazoline demonstrate similar safety and risk profiles in pediatric functional endoscopic sinus surgery However further prospective studies are needed to better evaluate the efficacy of topical epinephrine and confirm its…...

2+ week, 2+ day ago  (248+ words) A systematic review and meta-analysis published in journal of The Lancet Psychiatry suggests that cannabinoids may help reduce symptoms of certain substance use disorders (SUDs) and mental disorders, though the overall quality of evidence is low. Moderate-certainty evidence supports improved…...

2+ week, 4+ day ago  (241+ words) The exact mechanism underlying flexor tendon sheath ganglion (FTSG) formation remains unclear. Kazuhiro Kohata et al hypothesized that steroid injections into the A1 pulley are a cause of FTSG. They conducted a study to evaluate the risk of FTSG after steroid…...

2+ week, 4+ day ago  (374+ words) A recent clinical trial published in the Journal of the American Medical Association revealed transcutaneous electrical nerve stimulation (TENS) to significantly reduce movement-evoked pain in patients with fibromyalgia, with benefits sustained for up to 6 months. The findings support TENS as…...

2+ week, 4+ day ago  (265+ words) A new study published in the Journal of the American Medical Association showed that Diacerein did not reduce knee pain in patients with osteoarthritis (OA) and effusion-synovitis. Osteoarthritis of the knee is incapacitating and has few effective therapies. Patients with…...