News
Longer Persistence Seen With Upadacitinib vs TNFi in Rheumatoid Arthritis
5+ day, 2+ hour ago (245+ words) The risk for treatment discontinuation in patients with RA was lower among those receiving upadacitinib vs TNFi. HealthDay News — Patients with rheumatoid arthritis (RA) have longer persistence with upadacitinib than tumor necrosis factor inhibitors (TNFi), according to a study published…...
Rheumatoid Factor Positivity in PsA Linked to Poorer Outcomes, Biologic Discontinuation
4+ day, 23+ hour ago (510+ words) Learn about the clinical implications of rheumatoid factor positivity in psoriatic arthritis and its effect on biologic therapy discontinuation. Rheumatoid factor positivity is more common in psoriatic arthritis (PsA) than historically reported, and is associated with worse patient-reported outcomes, lower…...
Nonsurgical Procedure Tied to Improved Osteoarthritis-Related Knee Pain
3+ week, 4+ day ago (267+ words) Treatment with GAE with rapidly resorbable gelatin-based microspheres may be an effective option for knee pain in osteoarthritis. HealthDay News — For patients with osteoarthritis (OA)-related knee pain refractory to conservative treatment, genicular artery embolization (GAE) using rapidly resorbable gelatin-based…...
Re-Escalation of Anti-TNF Therapy Is Common in Older Adults With RA
3+ week, 6+ day ago (422+ words) Re-escalation of anti-TNF therapy is common among older adults with RA and typically occurs within 6 months of prior de-escalation. Among adults aged 66 years and older with rheumatoid arthritis (RA), antitumor necrosis factor (TNF) de-escalation is frequently followed by re-escalation in…...
Can a Telehealth Pain Skills Class Reduce Opioid Use for Chronic Pain?
1+ mon, 3+ week ago (194+ words) A single-session, virtually delivered pain relief skills class does not reduce opioid use among adults with chronic pain receiving long-term opioid therapy, according to study results published in The Journal of Pain. The primary study outcome was self-reported morphine-equivalent daily…...
Study Compares Short-Term Use of Cannabinoid Products for Chronic Pain
6+ mon, 6+ day ago (292+ words) THC/CBD mixed products slightly improved pain and increased dizziness, sedation, and nausea, while CBD alone may not increase harms. HealthDay News — Short-term treatment with comparable and high tetrahydrocannabinol (THC)-to-cannabidiol (CBD) ratio cannabinoid products may improve pain and increase…...
FDA Expands Caldolor Use to Include Postoperative Pain Management
2+ mon, 3+ week ago (154+ words) The Food and Drug Administration (FDA) has expanded the indications for Caldolor® (ibuprofen) injection to include the management of postoperative pain. Caldolor, a nonsteroidal anti-inflammatory drug (NSAID), is now approved for adults and pediatric patients aged 3 months and older for…...
Periprosthetic Joint Infections Linked to Increased Long-Term Mortality After THA
3+ mon, 2+ week ago (322+ words) The development of periprosthetic joint infection (PJI) is associated with more than double the risk of long-term mortality in patients undergoing a primary total hip arthroplasty (THA), according to study findings published in the Journal of Infection. Complications after THA…...
Global Burden of RA Is Rising Among Reproductive-Age Women
3+ mon, 6+ day ago (255+ words) The global burden of rheumatoid arthritis (RA) among women of childbearing age continues to rise, driven largely by demographic changes and widening regional disparities, despite only modest increases in incidence rates, according to findings from a global age-period-cohort analysis published…...
Defining the Complex Relationship Between Pollution and Autoimmunity
3+ mon, 2+ week ago (493+ words) Autoimmunity is considered a modern epidemic. Estimates show that as much as 10% of the population is now living with an autoimmune disease.1 We spoke with board-certified rheumatologist Anita Chandrasekaran, MD, MPH, to help understand why. “The incidence of autoimmune disease…...