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News
Unresectable Gallbladder Cancer Develops Rare Spontaneous
19+ hour, 16+ min ago (664+ words) Gallbladder cancer has produced an exceptionally rare and unsettling complication in a 65-year-old man: a spontaneous tunnel from the diseased organ to the skin, allowing a gallstone to emerge through the abdominal wall....
Long-term multimodal study reveals peripheral nerve involvement in
1+ day, 7+ hour ago (201+ words) This article reports a prospective 1-year study of peripheral nerve involvement in wild-type transthyretin amyloidosis (ATTRwt) cardiomyopathy. Key findings from the provided abstract: 23 patients with ATTRwt were compared with healthy controls. Small-fiber loss was common: abnormal intra-epidermal nerve fiber density…...
Study identifies potential multi-target treatment for chronic ankle
3+ day, 2+ hour ago (640+ words) Ankle sprains are often treated as temporary injuries, but for many people the consequences persist long after swelling and pain have subsided. As many as 70% of individuals who suffer an ankle sprain develop ongoing problems, including impaired balance, reduced proprioception,…...
Systematic review finds persistent inflammatory dysregulation in people
6+ day, 9+ hour ago (456+ words) Cerebral palsy has long been associated with disturbances that occur before, during, or shortly after birth, but a new systematic review suggests that the biological story may not end in the perinatal period....
Network meta-analysis compares local anesthetic techniques for pain relief
6+ day, 16+ hour ago (710+ words) during newborn circumcision Bioengineer.org...
Cannabis Use Associated With Earlier Psychosis Onset
1+ week, 1+ day ago (617+ words) Bioengineer.org...
Flexible Single-Source, Dual-Drive Knee Exoskeleton Assists Elderly Daily
1+ week, 2+ day ago (691+ words) The knee may soon become one of the most important targets for wearable robotics, as researchers in China have developed a flexible assistive exoskeleton designed to help older adults walk across ordinary outdoor environments....
Scientists discover brain mechanism that switches off chronic pain
1+ week, 2+ day ago (581+ words) At the base of the brain, a small but powerful cluster of nerve cells may hold the key to developing more precise treatments for chronic pain. Researchers at Washington University School of Medicine in St....
PARP1 Drives Neuropathic Pain Through GPX4-Dependent Ferroptosis in Injured
1+ week, 4+ day ago (604+ words) A molecular switch best known for helping cells respond to DNA damage may also be driving the burning, electric and persistent pain that follows nerve injury, according to a new study in nerve-injured mice. Researchers led by Y. Guo, L. Huang and…...
Molecular Clues Reveal Why Neuromas Cause Pain
2+ week, 1+ day ago (516+ words) Painful Nerve Growths Reveal a Molecular Switch Toward Extreme Sensitivity Peripheral nerves are built to repair themselves. After an injury, axons—the long, signal-carrying extensions of nerve cells—can grow outward in search of their original targets, guided by chemical…...