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News
Should we expect to live as long as our parents?
5+ hour, 28+ min ago (609+ words) Three cohorts of people with a centenarian parent were studied in one of the largest pieces of research into longevity to date. People with a parent who lived to 100 are likely to live longer, no matter what their lifestyle is…...
Phase III ARTEMIS-008 trial shows risvutatug rezetecan significantly improves overall survival in relapsed small-cell lung cancer
6+ hour, 39+ min ago (137+ words) B7-H3-directed antibody-drug conjugate reduced the risk of death by 54% compared with topotecan and improved progression-free survival and response rates At the June 6, 2026 data cutoff, after a median follow-up of 12.2 months, median overall survival was 18.5 months with Ris-Rez compared with 10.3 months…...
Tam-Peli meets primary endpoint for relapsed small-cell lung cancer in phase III trial
3+ hour, 8+ min ago (401+ words) The Clinical Trial Vanguard Tam-Peli meets primary endpoint for relapsed small-cell lung cancer in phase III trial Topotecan has been the default second-line chemotherapy for relapsed small-cell lung cancer for decades, and its survival benefit in that setting is modest…...
F. Hoffmann-La Roche Ltd | Globenewswire
9+ hour, 43+ min ago (230+ words) Roche’s collaborator MediLink announces phase III data for Tam-Peli showing significantly improved overall survival in Chinese patient population with relapsed small-cell lung cancer Key efficacy results from the phase III TAISHAN-302 trial1 Tam-Peli is designed to target B7-H3, a protein broadly expressed…...
Beyond the First-Line for ESR1-Mutated Disease
13+ hour, 32+ min ago (273+ words) An expert panel moderated by Sara Nunnery, MD, of Tennessee Oncology, convened to discuss how they choose therapy beyond the first-line setting for patients with ESR1-mutated disease. Dr. Nunnery was joined by Nan Chen, MD, of the University of Chicago;…...
Doctors Reach Pancreatic Tumor Through a Vein to Diagnose and Treat It
39+ min ago (625+ words) Pancreatic cancer remains one of the most formidable diagnoses in modern medicine, and a new case report is drawing attention for a strikingly inventive solution to one of its most stubborn clinical problems....
Aptamer-Guided CRISPR-Cas9 Delivery Could Make Cancer Genome Editing
3+ hour, 8+ min ago (55+ words) Gene editing has long promised a revolution in cancer medicine, yet the promise has remained stubbornly out of reach for one deceptively simple reason: getting the CRISPR-Cas9 machinery into tumor cells, and only tumor cells, is extraordinarily difficult. A new…...
FDA Clears CU Anschutz Clinical Trial Using Engineered Immune Cells to Fight Colorectal Cancer
2+ day, 21+ hour ago (836+ words) CAR T-cells developed at CU Anschutz will target two pathways that help colorectal tumors grow and evade the immune system AURORA, Colo., Sept. 10, 2026 /PRNewswire/ -- The U.S. Food and Drug Administration has granted permission for investigators at the University of Colorado Anschutz…...
Proteomic Aging Clocks Enter the Clinic in Landmark Phase 2a Geroprotection
5+ hour, 5+ min ago (744+ words) For decades, the central obstacle to testing therapies that slow human aging has been painfully simple: aging takes decades to measure. A drug that genuinely delays the biological processes of aging would need years, often a lifetime, of follow-up before…...
Mussel-Inspired Coating Keeps Tiny Artificial Lungs Clot-Free
7+ hour, 23+ min ago (676+ words) For the smallest and most fragile patients in intensive care, the difference between survival and decline often comes down to a few milliliters of oxygen. Preterm and term newborns who develop respiratory distress syndrome frequently need mechanical ventilation, and in…...