4+ day, 23+ min ago   (243+ words) Glioblastoma is a representative form of intractable brain cancer that frequently recurs even after surgery, radiation, and chemotherapy. Immune checkpoint inhibitors have shown only limited effect against the disease. One key reason is that immune cells that infiltrate the tumor…...

4+ day, 9+ hour ago   (389+ words) Roughly half the world’s population is infected with the stomach bacterium Helicobacter pylori, which is responsible for around 90 per cent of gastric cancers. However, until now, mystery has surrounded the question of why some H. pylori infections lead to a…...

6+ day, 7+ hour ago   (363+ words) Technology Networks Practically since its discovery, the highly contagious bacterium Clostridioides difficile (C diff) has been reported to not cause symptoms in infants and thus assumed that colonization was not a serious health issue In a new study, researchers at…...

1+ week, 8+ hour ago   (523+ words) When a patient has their DNA read, it gets compared against a reference version of the human genome. It allows geneticists and rare disease experts to look at a list of places where the patient's DNA differs. Most variations will…...

1+ week, 8+ hour ago   (330+ words) Researchers have identified a link between specific activities in gut bacteria and the liver disease PSC. The finding could explain a long-suspected connection between gut bacteria and PSC. It also opens up new treatment options. PSC stands for primary sclerosing…...

1+ week, 9+ hour ago   (1037+ words) Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed microscopic peptide droplets that deliver large amounts of gene-silencing molecules into cancer and immune cells, reducing the growth of hard-to-treat colorectal tumours by about 67 per cent in mice. The patent-pending…...

1+ week, 9+ hour ago   (354+ words) Ohio State experts are learning more about what causes gliomas to improve prevention, care and treatment. Median life expectancy following glioblastoma diagnosis is about 15 months with treatment, and only 5-7% of patients survive as long as five years. Treatment with radiation…...

1+ week, 18+ hour ago   (98+ words) technologynetworks.com Rising development costs, long clinical timelines, and high attrition rates in first-in-class discovery have renewed interest in drug repurposing as a way to extend the therapeutic value of existing medicines. For repurposed drugs that go on to gain…...

1+ week, 4+ day ago   (339+ words) Liver cancer is difficult to treat because tumors vary greatly from patient to patient. Researchers at the University of Basel have captured this diversity by creating a collection of mini-tumors, which they use to systematically search for new treatment options....

1+ week, 5+ day ago   (251+ words) Spatial transcriptomics is a powerful tool to create a detailed map of not just how genes are expressed in a piece of tissue, but also where genetic activity takes place in different cells and locations within the tissue. This is…...