4+ day, 11+ hour ago   (565+ words) An AI-powered imaging tool developed by Brainomix has been used to enrich data from a phase 2a trial of Endeavor BioMedicines' hedgehog pathway inhibitor taladegib, in development for idiopathic pulmonary fibrosis (IPF). The post hoc analysis of the study showed that…...

5+ day, 10+ hour ago   (809+ words) Drug development is an inherently risky endeavour, with the average probability of approval for a drug entering Phase I studies now sitting at just 6.7%. While much of this can be attributed to lack of efficacy, factors such as poor clinical…...

1+ week, 2+ day ago   (824+ words) This June marked the third such Women in AI event, taking place at a time when AI in medicine has progressed from pilot to infrastructure. Guest female speakers included: Dr Anushka Patchava, chief clinical & innovation officer, Cignpost; Nora Lamoudi-Sutcliffe, senior…...

1+ week, 4+ day ago   (499+ words) The UK's Medicines and Healthcare products Regulatory Agency (MHRA) has followed through on plans to roll out regional 'sandboxes' for NHS innovations, to operate alongside its centralised initiatives, via a partnership with Manchester University NHS Foundation Trust (MFT). MHRA's first…...

1+ week, 6+ day ago   (730+ words) Artificial intelligence (AI) is quietly reshaping pharmaceutical research. Driven by promises of faster trial design and drug discovery, the global AI-in-pharma market is projected to grow over 40% annually through 2030. Yet, for US drug developers, bringing these tools across the Atlantic…...

2+ week, 4+ day ago   (1596+ words) In the third and final part of this longevity series, I discuss how science discovers what extends life. Healthcare treats its failure, too late. In between these two sits the layer where outcomes are actually determined: daily behaviour. This is…...

2+ week, 5+ day ago   (227+ words) As clinical trials become more complex, sponsors face growing pressure to reach more representative patient populations while reducing participation burden and keeping studies moving without adding strain to sites. In the third episode of our PSCS leadership discussion series, developed…...

3+ week, 2+ day ago   (766+ words) Yet, despite all this measurement, site performance often doesn't improve. Why? Because measuring performance isn't the same as improving it. The question we should be asking is not, "Are we measuring site performance?" but, "Are the metrics we collect providing…...

3+ week, 3+ day ago   (381+ words) The Advanced Research Projects Agency for Health (ARPA-H) has awarded Siemens Healthineers up to $31.1 million over five years to accelerate the development of autonomous, remote, endovascular robotics. Siemens Healthineers believes a combination of endovascular robotics, image guidance, and dedicated devices…...

3+ week, 4+ day ago   (292+ words) New analysis from the Tufts Center for the Study of Drug Development (CSDD) and Palo Alto, CA-based Medable shows that AI agents accelerate clinical trials and improve staff productivity, delivering net financial gains to a sum as high as $21 million…...