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- 486articles · 30d
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News
Distinct EFEMP1 variants cause different forms of vision loss
1+ day, 8+ hour ago (248+ words) No name has been formally given for the newly discovered condition, but the researchers are referring to it as EFEMP1-associated late-onset retinal degeneration (L-ORD). It occurs due to the p.Arg140Trp variant in the EFEMP1 gene, which causes abnormally thick material to build…...
Targeted nanoparticles strengthen anti-cancer immune responses in tumors
1+ day, 9+ hour ago (165+ words) Adelaide University researchers have developed a new way of using mRNA technology to reprogram tumor-supporting immune cells and strengthen the body's anti-cancer immune response. Targeted nanoparticles strengthen anti-cancer immune responses in tumors Adelaide University researchers have developed a new way…...
Refined starch activates immune pathways after low-carb weight loss
2+ day, 7+ hour ago (344+ words) A controlled feeding trial reveals striking differences in how refined starch and added sugar affect immune cells after substantial weight loss on a very-low-carbohydrate diet. Study: Effects of refined carbohydrates on immune markers after weight loss on a very-low-carbohydrate diet:…...
Chronic interferon exposure drives immunosuppression in tumors
2+ day, 7+ hour ago (468+ words) Cancer biology and, in turn, cancer treatment have come a long way in the last few decades. Most people recognize this progress in breakthroughs like immunotherapy-a treatment strategy first deployed in 2011 that leverages the body's own immune cells to fight…...
New funding supports LMU research on pediatric inflammatory bowel disease
2+ day, 20+ hour ago (545+ words) The non-profit Boehringer Ingelheim Stiftung supports LMU clinician-scientist Daniel Kotlarz through its Rise up! program. New funding supports LMU research on pediatric inflammatory bowel disease The non-profit Boehringer Ingelheim Stiftung supports LMU clinician-scientist Daniel Kotlarz through its Rise up! program....
Evaluating new approaches for rare disease research
2+ day, 23+ hour ago (513+ words) Illumina spoke with its customer Marcel Nelen, head of the Genome Diagnostics department at the University Medical Center Utrecht (UMC Utrecht), one of eight academic centers supporting rare disease genomics research across the Netherlands. His team was among the first…...
Generative AI-driven drug Rentosertib enters Phase III trial for idiopathic pulmonary fibrosis
3+ day, 1+ hour ago (946+ words) Insilico Medicine, a clinical-stage biotechnology company powered by generative AI, today announced that it has dosed the first patient with Rentosertib (known as ISM001-055 / INS018_055) in GENESIS-IPF-3, a Phase III clinical trial (NCT07687459, CTR20262475) at Peking Union Medical College Hospital, while Shanghai Pulmonary Hospital…...
Gut microbiome may reveal inflammation and future disease risk better than age
3+ day, 5+ hour ago (585+ words) Why do some young adults already show inflammatory patterns usually seen decades later? A large microbiome study traces striking differences in immune and metabolic health to distinct communities of gut bacteria. Human gut microbiota composition is more strongly associated with…...
Protein-based MRI agent detects tiny lung cancer metastases
3+ day, 6+ hour ago (301+ words) "Lung cancer is often diagnosed only after it has spread, when treatment options become more limited," Yang said. "Our technology can detect tiny tumors and hidden metastases without exposing patients to radiation. It also helps reveal how aggressive a cancer…...
The link between PM2.5 and ADHD held up after researchers tested other explanations
3+ day, 8+ hour ago (260+ words) Two decades of nationwide data reveal contrasting patterns across birth outcomes, diabetes, and childhood ADHD as researchers probe whether the health effects associated with air pollution persist even as U.S. PM2.5 levels decline. Study: Long-term air pollution exposure and childhood ADHD prevalence....