1+ day, 5+ hour ago   (778+ words) The U.S. Food and Drug Administration this week granted permission for investigators at the University of Colorado Anschutz to conduct a clinical trial testing genetically engineered immune cells in adults with advanced colorectal cancer and pediatric patients with solid cancers who…...

1+ day, 5+ hour ago   (165+ words) Adelaide University researchers have developed a new way of using mRNA technology to reprogram tumor-supporting immune cells and strengthen the body's anti-cancer immune response. Targeted nanoparticles strengthen anti-cancer immune responses in tumors Adelaide University researchers have developed a new way…...

3+ day, 17+ hour ago   (400+ words) Researchers at Johns Hopkins Medicine have uncovered a critical biological mechanism that helps explain how inflammation is triggered and sustained in a wide range of diseases-highlighting a promising avenue for future therapeutic development. The study, published in PLOS One, identified…...

3+ day, 22+ hour ago   (320+ words) A team led by investigators from the University of Osaka uncovers cellular mechanisms that favor long-lived antibody responses, providing insights that may help researchers design vaccines that provide longer-lasting protection against infection. Study uncovers cellular mechanisms behind long-lasting antibody responses…...

4+ day, 2+ hour ago   (596+ words) This ability gives TCR therapy access to a much wider range of cancer targets - a big deal for solid tumors, since most of what makes those cells cancerous is hidden inside them, not on the surface. UCLA scientists have developed…...

5+ day, 3+ hour ago   (316+ words) Bacteria can survive antibiotics in several ways, including by pumping the drugs out of their cells before they can take effect. Scientists discover new mechanism for bacterial fosfomycin resistance Bacteria can survive antibiotics in several ways, including by pumping the…...

1+ week, 12+ hour ago   (208+ words) The body's heart muscle (for pumping blood), skeletal muscle (for movement and posture), and brown fat (for heat production), each require a lot of energy and make a lot of waste. And that waste needs to be managed. Now scientists…...

1+ week, 22+ hour ago   (295+ words) news-medical.net Autoimmune diseases form distinct genetic clusters, study finds Different autoimmune diseases often share genetic risk factors, but not through a single common genetic vulnerability. In a new study published in The Journal of Clinical Investigation, researchers from Karolinska…...

1+ week, 1+ day ago   (927+ words) As proteins are made in a cell, they are folded into the 3-D structure that allows them to work, but sometimes this process can go wrong. Misfolded proteins slip past cell cleanups and risk causing disease As proteins are made…...

1+ week, 4+ day ago   (166+ words) Senescent cells - cells that have stopped dividing but remain metabolically active - can accumulate with age and contribute to chronic inflammation and tissue dysfunction. A new Mini Review in Geromedicine examines a protein interaction that may help some of these cells…...