5+ day, 12+ hour ago   (488+ words) Researchers publishing in Aging Cell have described how stopping growth hormone receptor production in midlife significantly lengthens the lives of mice. Those mouse models, however, are genetically modified, with effects from birth. Bringing this into the clinic requires affecting growth…...

3+ week, 1+ day ago   (607+ words) A new study suggests that in amyotrophic lateral sclerosis – and possibly other neurodegenerative diseases – the brain’s immune cells devour stressed but still living neurons due to altered signaling [1]. The researchers started by investigating whether this machinery is actually engaged in…...

3+ week, 2+ day ago   (336+ words) Using cohort studies and a mouse model, researchers have found that the circulating factor ANGPTL8, which is produced by senescent fat cells, is related to age-related diseases and mortality in mice and people. [2] Ou, M. Y., Zhang, H., Tan, P. C., Zhou, S. B., & Li, Q. F. (2022). Adipose tissue aging:…...