5+ day, 9+ hour ago   (488+ words) Researchers publishing in Aging Cell have described how stopping growth hormone receptor production in midlife significantly lengthens the lives of mice. Those mouse models, however, are genetically modified, with effects from birth. Bringing this into the clinic requires affecting growth…...

1+ week, 4+ day ago   (869+ words) Properly untangling aging means untangling its various counterbalances, sometimes on the individual level. Here’s what’s been investigated this month. Wei-Wu He: People Should Become the CEOs of Their Own Health: Wei-Wu He is an unusual combination of scientist and businessman,…...

3+ week, 2+ day ago   (336+ words) Using cohort studies and a mouse model, researchers have found that the circulating factor ANGPTL8, which is produced by senescent fat cells, is related to age-related diseases and mortality in mice and people. [2] Ou, M. Y., Zhang, H., Tan, P. C., Zhou, S. B., & Li, Q. F. (2022). Adipose tissue aging:…...

4+ week, 1+ day ago   (492+ words) A massive human genetics study identified rare folliculin-interacting protein 1 (FNIP1) mutations associated with favorable metabolism and much lower cardiometabolic disease risk. Experiments in human liver cells and mice suggest a therapeutic route [1]. Importantly, that does not necessarily mean that genetics contributes…...