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@LifespanIO
lifespan.io > mice-with-growth-hormone-halted-in-middle-age-live-longer

Mice With Growth Hormone Halted in Middle Age Live Longer

6+ day, 14+ min ago   (488+ words) Researchers publishing in Aging Cell have described how stopping growth hormone receptor production in midlife significantly lengthens the lives of mice. Those mouse models, however, are genetically modified, with effects from birth. Bringing this into the clinic requires affecting growth…...

@LifespanIO
lifespan.io > how-old-fat-cells-trigger-inflammation-and-raise-risks

How Old Fat Cells Trigger Inflammation and Raise Risks

3+ week, 2+ day ago   (336+ words) Using cohort studies and a mouse model, researchers have found that the circulating factor ANGPTL8, which is produced by senescent fat cells, is related to age-related diseases and mortality in mice and people. [2] Ou, M. Y., Zhang, H., Tan, P. C., Zhou, S. B., & Li, Q. F. (2022). Adipose tissue aging:…...