7+ hour, 50+ min ago   (47+ words) EurekAlert! Prof. Caicun Zhou, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China. More on this News Release Late-breaking HARMONi-2 analysis shows ivonescimab significantly improves overall survival versus pembrolizumab in PD-L1-Positive Advanced NSCLC...

2+ day, 15+ hour ago   (189+ words) image: Oncoscience is a peer-reviewed, open-access, traditional journal covering the rapidly growing field of cancer research, especially emergent topics not currently covered by other journals. This journal has a special mission: freeing oncology from publication costs. It is free to…...

2+ day, 16+ hour ago   (461+ words) Credit: SUNY Upstate Medical University Upstate immunologist Mobin Karimi, MD/PhD, has been awarded a $3.3 million grant to explore a new type of immunotherapy to treat acute myeloid leukemia. The grant comes from the National Cancer Institute of the National…...

2+ day, 16+ hour ago   (301+ words) This stylized image illustrates the trajectories of brain cancer cells that were acquired in vivo over a period of 72 hours using the CloudScope. These cell trajectories are represented as colored trails, which are superimposed on the corresponding vasculature, depicted in…...

2+ day, 17+ hour ago   (224+ words) EurekAlert! A working model illustrating how red and blue light promote isoflavonoid biosynthesis in the roots of A. mongholicus. Astragalus mongholicus, a cornerstone of traditional Chinese medicine, produces isoflavonoids—bioactive compounds with anti-inflammatory, immune-boosting, and antiviral properties. However, the molecular machinery…...

2+ day, 19+ hour ago   (85+ words) In vivo immune cell engineering directly reprograms endogenous immune cells, bypassing individualized ex vivo manufacturing and opening a path toward more accessible and scalable cell therapies. This review summarizes cell-specific engineering strategies, compares viral and non-viral delivery platforms, highlights emerging…...

2+ day, 18+ hour ago   (548+ words) Salk Institute researchers define how chronic interferon exposure prompts a switch from anti-tumor activity to immunosuppression in mice, revealing a key target to sustain anti-tumor immune responses and combat immunotherapy-resistant cancer image: Representative images showing mitochondrial RNA (mtRNA) transcripts (red)…...

2+ day, 20+ hour ago   (346+ words) Lipid vesicles, liposomes, are artificial membranes that contain an aqueous interior surrounded by a bilayered lipid shell. The process allows for the creation of asymmetric LUV’s. This would allow for the inner and outer lipid layers to have different properties,…...

2+ day, 20+ hour ago   (164+ words) 5-year clinical trial in 1108 patients validates a new biodegradable stent strategy Credit: ©Science China Press Inspired by the Poisson raindrop question in mathematics, Professor Jiandong Ding at Fudan University derived a set of equations for the spatiotemporal evolution of random…...

3+ day, 2+ min ago   (298+ words) A test to determine if people who report out-of-body experiences could identify objects in another room produced results no better than chance, but afterward something strange happened: Two participants described, unprompted, researchers’ locations and activities behind closed doors. The participants…...