2+ day, 7+ hour ago   (274+ words) COLORECTAL cancer research has identified a core transcriptional regulatory circuitry involving MYC, ETS2 and FOXP1 that controls cancer type specific super enhancer activity and supports expression of key genes. The study reported that the master transcription factor MYC actively regulated super enhancer…...

3+ day, 7+ hour ago   (186+ words) The single-centre exploratory trial included 30 patients with stroke, who were randomly assigned to either an intervention group or a control group. Each group included 15 participants. Both groups demonstrated significant improvements in MMSE and MoCA scores. However, the researchers found no…...

3+ day, 7+ hour ago   (445+ words) DISTINCT changes in the lung microbiome and metabolism may be associated with progression from community-acquired pneumonia (CAP) to acute respiratory distress syndrome (ARDS) in children, according to new research. The study identified reduced microbial diversity and altered concentrations of dozens…...

4+ day, 7+ hour ago   (305+ words) EX VIVO cardiac simulators are emerging as a promising tool for personalised cardiovascular care, according to a new narrative review. These simulator platforms combine native cardiac tissue with mechanical circulatory systems to recreate physiologically relevant cardiac function and provide insights…...

4+ day, 7+ hour ago   (456+ words) RECEIVING immune checkpoint inhibitor therapy earlier in the day may be associated with substantially longer survival amongst patients with advanced cancer, according to new research. The large UK cohort study found that patients who received most of their immune checkpoint…...

5+ day, 7+ hour ago   (291+ words) EMJ This site is intended for healthcare professionals Biological Age Predicts Mortality in Cardio-Kidney-Metabolic Syndrome - Biological age acceleration was linked to higher mortality in CKM syndrome. - Phenotypic age acceleration was associated with greater mortality risk. - A mortality prediction model showed…...

5+ day, 7+ hour ago   (445+ words) EARLY initiation of statin therapy following a diagnosis of Type 2 diabetes may be associated with a lower risk of developing dementia, according to new research. The nationwide Danish study found that starting statins within 1 year of Type 2 diabetes diagnosis was…...

1+ week, 7+ hour ago   (473+ words) INCREASING body mass index (BMI) during childhood may contribute to poorer asthma control and declining lung function, according to findings from the All Age Asthma Cohort (ALLIANCE) study presented at the European Respiratory Society (ERS) Congress. The results suggest that…...

1+ week, 1+ day ago   (305+ words) EMJ This site is intended for healthcare professionals Dietary Fat Intake Linked to Survival in Prostate Cancer - Dietary fat intake was associated with long-term survival among patients with nonmetastatic prostate cancer. - Higher saturated fat intake was linked to 24% higher all-cause…...

1+ week, 1+ day ago   (278+ words) emjreviews.com This site is intended for healthcare professionals Epilepsy Study Links Antiseizure Drugs to Anticoagulant Risk - A study of adults with epilepsy receiving direct oral anticoagulants found outcome differences by antiseizure - Levetiracetam and strong enzyme inducing antiseizure medications were…...