2+ day, 20+ hour ago   (274+ words) COLORECTAL cancer research has identified a core transcriptional regulatory circuitry involving MYC, ETS2 and FOXP1 that controls cancer type specific super enhancer activity and supports expression of key genes. The study reported that the master transcription factor MYC actively regulated super enhancer…...

4+ day, 20+ hour ago   (305+ words) EX VIVO cardiac simulators are emerging as a promising tool for personalised cardiovascular care, according to a new narrative review. These simulator platforms combine native cardiac tissue with mechanical circulatory systems to recreate physiologically relevant cardiac function and provide insights…...

4+ day, 20+ hour ago   (408+ words) AI-Derived Whole-Body MRI Metrics Predict Myeloma Outcomes EMJ This site is intended for healthcare professionals AI-Derived Whole-Body MRI Metrics Predict Myeloma Outcomes - Exploratory study developed an AI pipeline to extract body composition metrics from whole-body MRI in multiple - Baseline muscle…...

1+ week, 3+ day ago   (324+ words) The study included patients from 55 sites across eight countries between 2015 and 2025. Participants had been diagnosed with prostate cancer within the previous 12 months, had recently started androgen deprivation therapy (ADT), or were due to begin ADT. Patients were randomly assigned to…...

1+ week, 5+ day ago   (278+ words) RAPID heart attack testing in patients with suspected myocardial infarction did not reduce emergency department length of stay despite demonstrating comparable safety to standard testing pathways, according to findings from the PRESC1SE-MI trial presented during the European Society of Cardiology…...

1+ week, 4+ day ago   (215+ words) AN INTERNATIONAL registry study has identified distinct clinical and serological associations with cancer in systemic sclerosis, showing that cancer timing and site relate differently to autoantibody status, smoking, and organ involvement, with implications for surveillance strategies. Cancer is a major…...

1+ week, 4+ day ago   (193+ words) Advanced ultrasound techniques that assess tissue stiffness and microvascular blood flow could improve differentiation between benign and nonbenign soft tissue tumours (STTs), according to new research. Researchers conducted a retrospective diagnostic accuracy study involving 167 consecutive patients referred for STT biopsy…...

1+ week, 4+ day ago   (1029+ words) This content was funded by Vitalograph. In a new Catalyst interview, Furat Shawki, Vice President, Digital Health Technologies, Vitalograph, explores a key question in clinical research: how can digital health technologies keep people at the centre, while helping the industry…...

2+ week, 20+ hour ago   (354+ words) MYOCARDIAL infarction classification has been simplified through a new universal definition that replaced numerical categories with three clinically meaningful groups, as per the newly release Fifth Universal Definition of Myocardial Infarction during the ESC Congress 2026.1 The new definition was jointly…...

2+ week, 20+ hour ago   (237+ words) HEPATOCELLULAR CARCINOMA surveillance faced important patient knowledge and accessibility challenges in the UK, with only 61.4% of surveyed patients reporting attendance every 6 months and just 15% correctly identifying liver cancer detection as the purpose of surveillance. A total of 832 patients participated. The…...