23+ hour, 51+ min ago   (1017+ words) A review of 57 studies reveals why music can ease pain, with personal choice, enjoyment, and active participation emerging as important factors. People put on music when something hurts, usually on the theory that it pulls attention away from the pain....

6+ day, 16+ hour ago   (1143+ words) Switching off a cluster of cells in the mouse brainstem eased nerve pain, and restoring one receptor reversed months of hypersensitivity. The brain runs a painkiller of its own. At the base of the skull, a small cluster of cells…...

2+ mon, 1+ day ago   (993+ words) Living with chronic migraines can turn ordinary days into a struggle. For many people, the pain comes with nausea, sensitivity to light and sound, and sometimes visual changes known as aura. Medicines help many patients, but they do not work…...

2+ mon, 6+ day ago   (783+ words) Long-term opioid use reshapes the brain’s reward system, dulling the pull of everyday pleasures until a shared laugh or a warm afternoon barely registers. Researchers call this loss of pleasure anhedonia, and it sits at the center of why opioid…...

2+ mon, 2+ week ago   (854+ words) Knee osteoarthritis usually follows a familiar path, with pain relievers, physical therapy, and cortisone injections easing symptoms for a while. However, many people eventually face the prospect of knee replacement surgery. A new procedure is beginning to fill the gap…...

2+ mon, 2+ week ago   (844+ words) Drug trials for knee arthritis have failed repeatedly, and for years the field shared a favorite explanation. The disease must be several different conditions in disguise, each running on its own biology. An international team built the largest study ever…...