4+ day, 6+ hour ago   (187+ words) Background: Sarcopenia, characterised by reduced skeletal muscle mass, is increasingly recognised as a determinant of postoperative morbidity in patients with malignancy. Evidence regarding its association with short-term outcomes after liver resection for malignant tumours remains limited in Bangladesh. Objective: This…...

1+ week, 3+ day ago   (340+ words) Background: Definitive radiotherapy represents a cornerstone treatment for localized prostate cancer, offering curative potential comparable to surgery. However, biochemical failure remains a concern, signaling possible disease progression. Objective: This study aimed to evaluate the frequency, timing, and predictors of biochemical…...

1+ week, 4+ day ago   (275+ words) Breast cancer with multiple organ metastases sometimes shows a discordant response to treatment depending on the site of the lesion. In addition, oncologists generally convert the treatment upon progression of a small part of metastatic lesions in a specific organ,…...

1+ week, 4+ day ago   (228+ words) Cancer remains the second leading cause of death in the United States, highlighting the need to strengthen the oncology workforce. Undergraduate medical education often lacks sufficient exposure to oncology, particularly radiation oncology, resulting in limited awareness of the specialty. Structured…...

1+ week, 4+ day ago   (311+ words) Background The increasing use of high-resolution imaging techniques in an aging society leads to an increased number of cystic pancreatic lesion diagnoses. In this study, we compared two patient groups who underwent surgery for a benign pancreatic cystic lesion, investigating…...

1+ week, 5+ day ago   (174+ words) Lymphadenopathy is a common presentation in urgent care and primary care settings and is most often due to benign or infectious causes. However, persistent or unexplained lymphadenopathy may represent an underlying malignancy, including Hodgkin lymphoma. We present the case of…...

1+ week, 6+ day ago   (209+ words) Cancer treatment is increasingly moving beyond single-agent strategies because tumor heterogeneity, clonal evolution, immune escape, and microenvironmental protection frequently limit durable disease control. Existing evidence remains fragmented across cancer types, treatment combinations, sequencing approaches, biomarker systems, and long-term safety outcomes,…...

1+ week, 6+ day ago   (201+ words) The Partner and Localizer of BRCA2 (PALB2) gene is a tumor suppressor gene with a role in DNA repair. Pathogenic autosomal dominant mutations of this gene significantly increase lifetime cancer risk, particularly breast and pancreatic cancers. We present a case of a…...

1+ week, 6+ day ago   (325+ words) Idiopathic pulmonary fibrosis is a chronic, progressive fibrosing interstitial lung disease with a poor prognosis, carrying a median survival of two to three years without antifibrotic therapy. Nintedanib, an oral intracellular tyrosine kinase inhibitor (TKI) targeting vascular endothelial growth factor…...

2+ week, 6+ hour ago   (224+ words) An octogenarian woman with Merkel cell carcinoma of the right upper arm, staged as Stage IIIA at initial diagnosis, underwent wide local excision with sentinel lymph node biopsy followed by adjuvant radiation therapy. She later developed regional nodal recurrence requiring…...