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Long-term multimodal study reveals peripheral nerve involvement in
2+ week, 5+ day ago (201+ words) This article reports a prospective 1-year study of peripheral nerve involvement in wild-type transthyretin amyloidosis (ATTRwt) cardiomyopathy. Key findings from the provided abstract: 23 patients with ATTRwt were compared with healthy controls. Small-fiber loss was common: abnormal intra-epidermal nerve fiber density…...
PARP1 Drives Neuropathic Pain Through GPX4-Dependent Ferroptosis in Injured
4+ week, 1+ day ago (604+ words) A molecular switch best known for helping cells respond to DNA damage may also be driving the burning, electric and persistent pain that follows nerve injury, according to a new study in nerve-injured mice. Researchers led by Y. Guo, L. Huang and…...